ABSTRACT
Objective: To determine severity and mortality risk factors in patients admitted to hospital for COVID 19 in the population of Ourense. Method: Prospective study in 342 patients hospitalized at the University Hospital of Ourense for COVID 19 between March 8 and May 15, 2020, the period corresponding to the first wave of infections. Demographic variables, pathologies and previous treatments, laboratory tests and treatments during admission were collected and were related to the risk of admission to critical patients and mortality. A univariate analysis and a multivariate logistic regression analysis were carried out. For the comparison of qualitative variables, the Chi-square test was used. For the comparison of the quantitative variables, the normality of the distribution of the data in each of the sample groups was analyzed and the t-Student or Mann-Whitney test was applied. The accepted level of significance for all hypothesis tests was 0.05. Results and Conclusions: Age> 75, lymphocytes <0.9, D-dimer> 2500 were positively correlated with mortality. Obesity, lymphocytes <0.8, Ddimer> 2500, LDH> 500 and ferritin> 800 were positively correlated with the risk of admission to critical patients. Treatment with Lopinavir/Ritonavir, Hydroxychloroquine, corticosteroids, and anticoagulants acted as protective factors against mortality.